Primary Large B Cell Lymphoma in the Tibia of an Old Individual Relapsing at an Uncommon Location

Involvement of the bones is a rare presentation of diffuse large B cell non-Hodgkin’s lymphoma and afects mostly jounger individuals. The tibia, as the initial site of the disease is a rather ucomon target, particularly when it emerges at older age. We present a 94 old individual with large B-cell lymphoma stage IV E that involved the right upper tibia treated by CHOP-R and that relapsed one year later at the right testicle. The rarity of bone invivment, the old age and the unusual site of relaps are disussed.

Keywords: Large B-cell lymphoma, bones, tibia, testicle, CHOP, rituximab, bendamustine.